{"id":35964,"date":"2025-07-07T17:06:55","date_gmt":"2025-07-07T17:06:55","guid":{"rendered":"https:\/\/todaysveterinarypractice.com\/?p=35964"},"modified":"2025-07-08T15:19:06","modified_gmt":"2025-07-08T15:19:06","slug":"what-veterinarians-need-to-know-about-screwworms","status":"publish","type":"post","link":"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/parasitology\/what-veterinarians-need-to-know-about-screwworms\/","title":{"rendered":"What Veterinarians Need to Know About Screwworms"},"content":{"rendered":"<p><span style=\"font-weight: 400\">Known as the primary screwworm, <\/span><i><span style=\"font-weight: 400\">Cochliomyia hominivorax<\/span><\/i><span style=\"font-weight: 400\"> causes myiasis and its geographical range extends through Central and South America. Adult flies lay eggs in fresh wounds and hatch quickly, usually within 24 hours, fully developing within a week.<\/span><span style=\"font-weight: 400\"><sup>1<\/sup><\/span><span style=\"font-weight: 400\"> The larvae feed on living tissue and may be fatal if left untreated.<\/span><span style=\"font-weight: 400\"><sup>1<\/sup><\/span><span style=\"font-weight: 400\"> Females mate once in their lifetime and environmental control is typically through the release of sterile male flies. This can effectively break the lifecycle and limit further infestations.<\/span><span style=\"font-weight: 400\"><sup>1-3<\/sup><\/span><\/p>\n<p><span style=\"font-weight: 400\">Current concerns in the United States regarding the primary screwworm center around infested cattle in Mexico.<\/span><span style=\"font-weight: 400\"><sup>3<\/sup><\/span><span style=\"font-weight: 400\"> The close proximity to the United States has put many on alert; increased monitoring of livestock, wildlife, and pets is recommended. The most at-risk include those closest to the border or those moving between Mexico and the United States.\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400\">This article will address some of the most common questions general practitioners might have about this parasite of increasing concern.<\/span><\/p>\n<h3><b>What causes infestations and which hosts are vulnerable?<\/b><\/h3>\n<p><span style=\"font-weight: 400\">Most vertebrate hosts, including humans, are susceptible to screwworm infestations. Any fresh wound (e.g., castration, ear or tail docking, newborn navel, branding, shearing cuts, tick bites, cuts, abrasions) or mucus membrane (e.g., nostril, ears, mouth) can serve as a potential site for egg laying by a female fly.<\/span><span style=\"font-weight: 400\"><sup>1-4<\/sup><\/span><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n<h3><b>How does it harm the host?\u00a0<\/b><\/h3>\n<p><span style=\"font-weight: 400\">Once eggs hatch, larvae feed on living tissue (obligate myiasis), including bone. They feed as they develop through their larval stages. Within 3 days of infestation, larvae (maggots) should be visible. They will start small and gradually increase in size to a third instar larva (<\/span><b>FIGURE 1<\/b><span style=\"font-weight: 400\">). Wounds will enlarge and get worse, have a foul odor, and larvae (maggots) may be visible. In many instances, the development of necrotic tissue associated with these wounds and screwworm infestations will attract other flies, and larvae from additional fly species will begin to feed on the surrounding dead tissue (facultative myiasis).<\/span><span style=\"font-weight: 400\"><sup>1-4<\/sup><\/span><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n<div id=\"attachment_35968\" style=\"width: 434px\" class=\"wp-caption aligncenter\"><img fetchpriority=\"high\" decoding=\"async\" aria-describedby=\"caption-attachment-35968\" class=\" wp-image-35968\" src=\"https:\/\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-1-300x241.png\" alt=\"Cochliomyia hominivorax, primary screwworm, third instar larva (10x magnification). \" width=\"424\" height=\"340\" srcset=\"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-1-300x241.png 300w, https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-1-1024x821.png 1024w, https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-1-768x616.png 768w, https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-1.png 1152w\" sizes=\"(max-width: 424px) 100vw, 424px\" \/><p id=\"caption-attachment-35968\" class=\"wp-caption-text\">Figure 1. <em>Cochliomyia hominivorax<\/em>, primary screwworm, third instar larva (10x magnification).<\/p><\/div>\n<h3><b>How are screwworm infestations diagnosed?\u00a0<\/b><\/h3>\n<p><span style=\"font-weight: 400\">Screwworm larvae are diagnosed based on distinguishing morphological characteristics. One of the most notable characteristics are the dark tracheal trunks (<\/span><b>FIGURE 2<\/b><span style=\"font-weight: 400\">) extending from spiracular plates (<\/span><b>FIGURE 3<\/b><span style=\"font-weight: 400\">), which allow the larvae to breathe while consuming tissue.<\/span><span style=\"font-weight: 400\"><sup>2<\/sup><\/span><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n<div class=\"su-image-carousel  su-image-carousel-has-spacing su-image-carousel-crop su-image-carousel-crop-1-1 su-image-carousel-has-lightbox su-image-carousel-has-outline su-image-carousel-adaptive su-image-carousel-slides-style-default su-image-carousel-controls-style-dark su-image-carousel-align-center\" style=\"max-width:350px\" data-flickity-options='{\"groupCells\":true,\"cellSelector\":\".su-image-carousel-item\",\"adaptiveHeight\":false,\"cellAlign\":\"left\",\"prevNextButtons\":true,\"pageDots\":false,\"autoPlay\":5000,\"imagesLoaded\":true,\"contain\":true,\"selectedAttraction\":0.025,\"friction\":0.28}' id=\"su_image_carousel_69d37d534b95b\"><div class=\"su-image-carousel-item\"><div class=\"su-image-carousel-item-content\"><a href=\"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-2.png\" target=\"_blank\" rel=\"noopener noreferrer\" data-caption=\"Figure 2. Cochliomyia hominivorax, primary screwworm, dark tracheal trunks of third instar larva (40x magnification).\"><img decoding=\"async\" width=\"1024\" height=\"821\" src=\"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-2-1024x821.png\" class=\"\" alt=\"Cochliomyia hominivorax, primary screwworm, dark tracheal trunks of third instar larva (40x magnification).\" srcset=\"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-2-1024x821.png 1024w, https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-2-300x241.png 300w, https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-2-768x616.png 768w, https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-2.png 1152w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><span>Figure 2. Cochliomyia hominivorax, primary screwworm, dark tracheal trunks of third instar larva (40x magnification).<\/span><\/a><\/div><\/div><div class=\"su-image-carousel-item\"><div class=\"su-image-carousel-item-content\"><a href=\"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-3.png\" target=\"_blank\" rel=\"noopener noreferrer\" data-caption=\"Figure 3. Cochliomyia hominivorax, primary screwworm, spiracular plates of third instar larva (80x magnification).\"><img decoding=\"async\" width=\"1024\" height=\"821\" src=\"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-3-1024x821.png\" class=\"\" alt=\"Cochliomyia hominivorax, primary screwworm, spiracular plates of third instar larva (80x magnification).\" srcset=\"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-3-1024x821.png 1024w, https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-3-300x241.png 300w, https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-3-768x616.png 768w, https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2025\/07\/Walden_Screwworms-Figure-3.png 1152w\" sizes=\"(max-width: 1024px) 100vw, 1024px\" \/><span>Figure 3. Cochliomyia hominivorax, primary screwworm, spiracular plates of third instar larva (80x magnification).<\/span><\/a><\/div><\/div><\/div><script id=\"su_image_carousel_69d37d534b95b_script\">if(window.SUImageCarousel){setTimeout(function() {window.SUImageCarousel.initGallery(document.getElementById(\"su_image_carousel_69d37d534b95b\"))}, 0);}var su_image_carousel_69d37d534b95b_script=document.getElementById(\"su_image_carousel_69d37d534b95b_script\");if(su_image_carousel_69d37d534b95b_script){su_image_carousel_69d37d534b95b_script.parentNode.removeChild(su_image_carousel_69d37d534b95b_script);}<\/script>\n<p><span style=\"font-weight: 400\">Look for larvae (maggots) and smelly wounds that are increasing in size and not healing. Animals may be painful, not eating, and\/or lethargic.<\/span><span style=\"font-weight: 400\"><sup>3,4<\/sup><\/span><span style=\"font-weight: 400\">\u00a0<\/span><\/p>\n<h3><b>Is there a treatment for screwworm infestations?\u00a0<\/b><\/h3>\n<p><span style=\"font-weight: 400\">Environmentally, the release of sterile males to mate with female flies and break the lifecycle is the best approach to overall management.<\/span><span style=\"font-weight: 400\"><sup>1-4<\/sup><\/span><span style=\"font-weight: 400\"> On a host, removal of larvae (maggots) and wound care is essential. Make sure to use gloves while cleaning wounds and handling larvae. Larvae should be preserved in 70% ethyl alcohol or isopropanol.<\/span><span style=\"font-weight: 400\"><sup>3,4<\/sup><\/span><span style=\"font-weight: 400\"> The use of insecticides or off-label ivermectin have been reported, but efficacy has not been proven.<\/span><span style=\"font-weight: 400\"><sup>3<\/sup><\/span><span style=\"font-weight: 400\"> Off-label use of nitenpyram,<\/span><span style=\"font-weight: 400\"><sup>5<\/sup><\/span><span style=\"font-weight: 400\"> spinosad,<\/span><span style=\"font-weight: 400\"><sup>6<\/sup><\/span><span style=\"font-weight: 400\"> lotilaner,<\/span><span style=\"font-weight: 400\"><sup>7<\/sup><\/span><span style=\"font-weight: 400\"> afoxolaner,<\/span><span style=\"font-weight: 400\"><sup>8<\/sup><\/span><span style=\"font-weight: 400\"> and sarolaner,<\/span><span style=\"font-weight: 400\"><sup>9<\/sup><\/span><span style=\"font-weight: 400\"> has shown efficacy at expelling larvae within 2 to 6 hours after treatment and larval death within 24 hours post-treatment. Prevention or treatment of secondary bacterial infections may also be necessary.\u00a0<\/span><\/p>\n<h3><b>Can a host survive infestation?\u00a0<\/b><\/h3>\n<p><span style=\"font-weight: 400\">This will depend on the severity of infestation and speed of intervention.\u00a0<\/span><\/p>\n<h3><b>How can infestations be prevented in companion animals?\u00a0<\/b><\/h3>\n<p><span style=\"font-weight: 400\">The best way to prevent screwworm infestations is to be knowledgeable and aware of risks, especially if traveling to endemic areas. Properly treat and manage any wounds and seek care if there are any nonhealing wounds or if fly larvae (maggots) are noticed on a wound. Keep animals indoors, if possible, to minimize exposure to egg-laying female flies. Additionally, if going outdoors, use insect repellents and note that, although off-label, systemic insecticides may also be helpful in limiting potential infestations.<\/span><span style=\"font-weight: 400\"><sup>3,4<\/sup><\/span><\/p>\n<h3><b>Who should be alerted to a potential infestation?\u00a0<\/b><\/h3>\n<p><span style=\"font-weight: 400\">Veterinarians should contact their state animal health official or veterinarian as well as the USDA Animal and Plant Health Inspection Service (<a href=\"https:\/\/www.aphis.usda.gov\/labs\/diagnostic-testing\">aphis.usda.gov\/labs\/diagnostic-testing<\/a>). Suspected samples can be sent to the National Veterinary Services Laboratory in Ames, Iowa.<\/span><span style=\"font-weight: 400\"><sup>3,4<\/sup><\/span><span style=\"font-weight: 400\">\u00a0\u00a0<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This FAQ addresses some of the most common questions general practitioners might have about this parasite of increasing concern.<\/p>\n","protected":false},"author":693,"featured_media":35975,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"iawp_total_views":3206,"footnotes":""},"categories":[342],"tags":[],"class_list":["post-35964","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-digital-exclusive","column-parasitology","clinical_topics-parasitology"],"acf":{"hide_sidebar":false,"hide_sidebar_ad":false,"hide_all_ads":false},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.7 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