{"id":35481,"date":"2025-02-17T16:57:53","date_gmt":"2025-02-17T16:57:53","guid":{"rendered":"https:\/\/todaysveterinarypractice.com\/?p=35481"},"modified":"2025-02-17T16:57:53","modified_gmt":"2025-02-17T16:57:53","slug":"water-water-everywhere","status":"publish","type":"post","link":"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/personal-professional-development\/water-water-everywhere\/","title":{"rendered":"\u201cWater, Water Everywhere\u201d"},"content":{"rendered":"

As veterinarians, we are very aware of the health dangers posed by leptospirosis to our patients. First identified in 1886 by Adolf Weil, who described severe cases of jaundice, kidney failure, and fever in humans, it was subsequently named Weil\u2019s disease and was often associated with outdoor occupations in which people encountered water, such as sewer workers, rice-field workers, and coal miners. The World Health Organization estimates there to be more than 1 million human leptospirosis cases annually, with mortality rates reaching 20% in untreated individuals. Leptospirosis disproportionately affects disadvantaged socioeconomic communities that are most vulnerable to outbreaks of zoonotic diseases, primarily due to contact with infected animals and contaminated soil and water. Urbanization, climate change, and extreme weather events have heightened exposure to polluted waters, making it likely to remain a frontline concern for us, our patients, and our clients. In this issue, Dr. Jane E. Sykes presents an up-to-date <\/span>review on leptospirosis<\/span><\/a> in our companion animal patients.<\/span><\/p>\n

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What We\u2019re Reading<\/span><\/h3>\n

In each issue, a member of our Editorial Advisory Board will share a recent open access publication of interest.<\/i><\/p>\n

Dietary Magnesium Supplementation in Cats With Chronic Kidney Disease: A Prospective Double-Blind Randomized Controlled Trial
\n<\/b><\/span>Tang PK, van den Broek DHN, Jepson RE, et al.
\n<\/span>doi:10.1111\/jvim.17134<\/i><\/span><\/a><\/p>\n

What Was Investigated?<\/b><\/span> This study evaluated the effects of a short-term (4-month), magnesium-enriched, phosphate-restricted diet (PRD) in cats with chronic kidney disease (CKD). The purpose was to determine whether dietary magnesium supplementation could influence plasma total magnesium (tMg), ionized calcium (iCa), and fibroblast growth factor 23 (FGF23) concentrations since increased iCa and FGF23 concentrations are associated with progression of CKD in cats, and increased tMg has been shown to lower these concentrations.<\/p>\n

What Was Found? <\/b><\/span>The study enrolled 60 cats with CKD and divided them into 2 groups: 27 in the magnesium-enriched PRD group and 33 in the control PRD group. Cats on the magnesium-enriched diet showed a significant increase in tMg levels over time. The magnesium-enriched diet group was less likely to have an increase in iCa while its FGF23 concentrations remained stable.<\/p>\n

Take-Home Points<\/b><\/p>\n