{"id":16972,"date":"2019-06-21T18:38:59","date_gmt":"2019-06-21T18:38:59","guid":{"rendered":"https:\/\/todaysveterinarypractice.com\/?p=16972"},"modified":"2022-02-21T14:26:31","modified_gmt":"2022-02-21T14:26:31","slug":"a-potential-game-changer-for-pets-with-diabetes","status":"publish","type":"post","link":"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/endocrinology\/a-potential-game-changer-for-pets-with-diabetes\/","title":{"rendered":"A Potential Game Changer for Pets with Diabetes"},"content":{"rendered":"<p>When Olaf, a four-year-old Siberian husky, was diagnosed with diabetes in February, there wasn\u2019t anything his owners, Gina and Brian Dacey, wouldn\u2019t do to help him. \u201cWe\u2019ve had him since he was a few weeks old, and he\u2019s really still just a baby,\u201d Gina Dacey said.<\/p>\n<p><a href=\"https:\/\/www.avma.org\/public\/PetCare\/Pages\/Diabetes-in-Pets.aspx\">Pets with diabetes<\/a> cannot properly use glucose\u2014a type of sugar found in the blood and the main source of energy for all the body\u2019s cells. Glucose levels are primarily controlled by a hormone called insulin, which in pets with diabetes is either not produced or is insufficient for healthy living. Diabetic animals, just like many humans with the condition, must receive carefully timed daily injections of insulin to avoid developing life-threatening complications from their disease.<\/p>\n<p>Already juggling the schedules of two small children and work, the couple rearranged their life to ensure someone would always be home to give Olaf his twice-daily insulin injections. \u201cIt\u2019s definitely been a lifestyle change and learning curve for all of us\u2014especially Olaf, who\u2019s used to getting treats from his human sister,\u201d Dacey said. \u201cNow my three-year-old daughter will tell him, \u2018You can\u2019t have a treat, because you have diabetes and we have to watch your blood sugar.\u2019\u201d<\/p>\n<p>However, despite the family\u2019s best efforts, Olaf\u2019s blood-sugar levels proved difficult to normalize, and the husky developed cataracts, a complication of his uncontrolled disease. \u201cOn Easter, I called his veterinarian sobbing because we noticed he was having trouble seeing,\u201d Dacey recalled. \u201cI didn\u2019t know what to do, because everything we had tried\u2014insulin adjustments, longer and more frequent exercising\u2014wasn\u2019t helping enough.\u201d<\/p>\n<p>Her veterinarian suggested that a longer-acting insulin might offer better blood-sugar control. While Dacey was researching options\u2014learning that these products for humans can be purchased for pets\u2014she stumbled across a <a href=\"https:\/\/trials.vet.tufts.edu\/clinical_trials\/a-pilot-study-to-evaluate-the-efficacy-of-an-ultralong-acting-insulin-in-canine-diabetes\/\">free clinical trial<\/a> of a new ultra-long-lasting insulin for dogs. For the study at Cummings Veterinary Medical Center, veterinarian Orla Mahony is investigating whether a new insulin can control glucose levels in dogs using a single weekly injection.<\/p>\n<p>Although diabetes is already usually very treatable in companion animals, \u201chaving a diabetic pet is a big commitment for any owner, and it\u2019s not doable for everyone,\u201d explained Mahony, a board-certified small-animal internist who specializes in endocrinology. \u201cDiabetic pets typically require an insulin injection twice daily, and those injections are timed\u2014they are not just given whenever you happen to be at home. That has an enormous impact on pet owners, who can no longer work late or sleep in on the weekends. For people who need to travel a lot for work, it can be an especially huge issue.\u201d<\/p>\n<p>The new insulin \u201cis potentially a game changer,\u201d said Mahony, a clinical assistant professor at Cummings School. \u201cIf it\u2019s successful, owners could give their pets an injection just once a week, removing the need to be home at the same time every day,\u201d she said. \u201cAnd although the majority of pets take their shots without a bother, some pets really fight them, so reducing the number of injections would improve quality of life for these animals and their owners. We also think that using an ultra-long acting insulin will lead to better control of pets\u2019 diabetes.\u201d<\/p>\n<p>In the Cummings School study, dogs with stable diabetes that are otherwise healthy receive four weekly injections of the new insulin, administered at the Foster Hospital. If it\u2019s effective in their pet, owners then will have the option of continuing to use the insulin at home for a year after the trial ends.<\/p>\n<p>In addition to this clinical trial, which is part of a multi-institutional study that includes UC Davis School of Veterinary Medicine, Mahony is working to launch a trial of a weekly insulin injection designed for cats. Both insulins were created by a Massachusetts biopharmaceutical company that develops products for human and veterinary medicine. Currently, long-lasting insulins are available in human medicine, but the injections only control blood-sugar levels for two or three days, according to Mahony.<\/p>\n<p>After reading about the Tufts clinical trial, Dacey applied to enroll Olaf, and soon after the husky received the ultra-long-lasting insulin as the first case in the study. Dacey said Olaf is doing much better on the new treatment. \u201cHis personality has improved,\u201d she said. \u201cHe has so much more energy that we went out for a run this morning\u2014something that wasn\u2019t possible when his sugars were not well controlled.\u201d<\/p>\n<p>To learn more about participating in the diabetes clinical trials at Cummings School of Veterinary Medicine, email clinicaltrials@tufts.edu.<\/p>\n<p>This article was reprinted from\u00a0<a href=\"https:\/\/now.tufts.edu\/articles\/potential-game-changer-pets-dogs-cats-diabetes\">now.tufts.edu<\/a>\u00a0with permission from\u00a0Taraneh Pettinato, Associate Director of Media Relations, Cummings School of Veterinary Medicine at Tufts University.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Four-year-old Siberian husky Olaf was diagnosed with diabetes.<\/p>\n","protected":false},"author":9,"featured_media":16973,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"iawp_total_views":198,"footnotes":""},"categories":[342],"tags":[],"class_list":["post-16972","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-digital-exclusive","column-digital-exclusive","clinical_topics-endocrinology","clinical_topics-news"],"acf":{"hide_sidebar":false,"hide_sidebar_ad":false,"hide_all_ads":false},"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v24.7 (Yoast SEO v27.3) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>A Potential Game Changer for Pets with Diabetes<\/title>\n<meta name=\"description\" content=\"Siberian husky Olaf was diagnosed with diabetes. 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When nothing helped control the disease, Olaf&#039;s vet discovered a promising clinical trial at Cummings VMC.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/endocrinology\/a-potential-game-changer-for-pets-with-diabetes\/\" \/>\n<meta property=\"og:site_name\" content=\"Today&#039;s Veterinary Practice\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/todaysveterinarypractice\" \/>\n<meta property=\"article:published_time\" content=\"2019-06-21T18:38:59+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-02-21T14:26:31+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/wp-content\/uploads\/sites\/4\/2019\/06\/Olaf_diabetes_MattWrightPhoto.png\" \/>\n\t<meta property=\"og:image:width\" content=\"864\" \/>\n\t<meta property=\"og:image:height\" content=\"576\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"Sandy Walsh, RVT, CVPM\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Sandy Walsh, RVT, CVPM\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"4 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/endocrinology\\\/a-potential-game-changer-for-pets-with-diabetes\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/endocrinology\\\/a-potential-game-changer-for-pets-with-diabetes\\\/\"},\"author\":{\"name\":\"Sandy Walsh, RVT, CVPM\",\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/#\\\/schema\\\/person\\\/a23b723e80e334bfb601dfa22ef8e6cd\"},\"headline\":\"A Potential Game Changer for Pets with Diabetes\",\"datePublished\":\"2019-06-21T18:38:59+00:00\",\"dateModified\":\"2022-02-21T14:26:31+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/endocrinology\\\/a-potential-game-changer-for-pets-with-diabetes\\\/\"},\"wordCount\":799,\"publisher\":{\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/endocrinology\\\/a-potential-game-changer-for-pets-with-diabetes\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/wp-content\\\/uploads\\\/sites\\\/4\\\/2019\\\/06\\\/Olaf_diabetes_MattWrightPhoto.png\",\"articleSection\":[\"Digital Exclusive\"],\"inLanguage\":\"en-US\"},{\"@type\":[\"WebPage\",\"MedicalWebPage\"],\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/endocrinology\\\/a-potential-game-changer-for-pets-with-diabetes\\\/\",\"url\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/endocrinology\\\/a-potential-game-changer-for-pets-with-diabetes\\\/\",\"name\":\"A Potential Game Changer for Pets with Diabetes\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/endocrinology\\\/a-potential-game-changer-for-pets-with-diabetes\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/endocrinology\\\/a-potential-game-changer-for-pets-with-diabetes\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarypractice.com\\\/wp-content\\\/uploads\\\/sites\\\/4\\\/2019\\\/06\\\/Olaf_diabetes_MattWrightPhoto.png\",\"datePublished\":\"2019-06-21T18:38:59+00:00\",\"dateModified\":\"2022-02-21T14:26:31+00:00\",\"description\":\"Siberian husky Olaf was diagnosed with diabetes. 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