{"id":15739,"date":"2019-01-05T12:57:01","date_gmt":"2019-01-05T12:57:01","guid":{"rendered":"https:\/\/todaysveterinarypractice.com\/?p=15739"},"modified":"2022-02-21T15:20:50","modified_gmt":"2022-02-21T15:20:50","slug":"veterinary-schools-receive-grants-to-treat-cancer-in-dogs","status":"publish","type":"post","link":"https:\/\/navc.sitepreview.app\/todaysveterinarypractice.com\/news\/veterinary-schools-receive-grants-to-treat-cancer-in-dogs\/","title":{"rendered":"Veterinary Schools Receive Grants to Treat Cancer in Dogs"},"content":{"rendered":"

Five veterinary schools are receiving research grants from the V Foundation for Cancer Research<\/a> in an innovative grant-making program that aims to accelerate research in the field of comparative oncology. Canine comparative oncology enables researchers from human and veterinary medicine to explore new cancer therapies for humans and dogs. As part of the program, the veterinary schools will work with cancer centers that treat people.<\/p>\n

Researchers will explore treatments that will have better success and less toxicity for dogs and people, according to a news release from The V Foundation The foundation was founded by Jim Valvano \u2014 nicknamed Jimmy V \u2014 the late North Carolina State basketball coach, who died in 1993 after being diagnosed with adenocarcinoma.<\/p>\n

Canine Comparative Oncology: “A Simple Idea”<\/h3>\n

Canine tumors often share multiple characteristics with human cancers, including responses to specific therapies. Some of the most prevalent cancers diagnosed in humans and dogs include sarcomas, melanoma, lymphomas, breast and bladder cancer. Cancer is the leading cause of death in dogs, with 1 in 4 developing the disease in his or her lifetime; while for humans, it\u2019s 1 in 3.<\/p>\n

\u201cCanine comparative oncology is a simple idea,\u201d says William Eward, M.D., a surgical oncologist at Duke Cancer Institute<\/a>. \u201cTo understand cancer, we shouldn\u2019t just study it in one species any more than we should study it in one person. By seeing what features a specific cancer displays not only across individuals but also across species, we can understand what are the key \u2018drivers\u2019 of that cancer.\u201d<\/p>\n

Researchers are emphasizing that they are not using research dogs; rather, they are treating and studying client-owned dogs.<\/p>\n

\u201cPet dogs, specifically, are valuable for several reasons,\u201d explains Eward. \u201cFirst, there are quite a few cancers \u2014 such as osteosarcoma \u2014 that are far more common in dogs than in people. This gives us a better opportunity to encounter more patients than we would by studying humans alone. Second, because a dog\u2019s life plays out in shorter periods of time than a human\u2019s life, we can make discoveries more quickly. Third, comparative oncology provides benefits to both humans and dogs.<\/p>\n

Man’s Best Friend<\/h3>\n

For every human child with osteosarcoma, there are at least 50 dogs with osteosarcoma. Dogs share our environment and have nearly identical immune systems, says Eward, so by studying dogs with sarcoma, we can learn more about this type of cancer and also have the opportunity to help \u201cman\u2019s best friend.\u201d<\/p>\n

The V Foundation, based in Cary, N.C., has awarded more than $700,000 in the past three years for canine comparative oncology research. More than $200 million in cancer research grants have been awarded since 1993, when Valvano founded the organization.<\/p>\n

Consortium for Canine Comparative Oncology<\/h3>\n

Duke and North Carolina State University have formed the Consortium for Canine Comparative Oncology<\/a>, or C3O, which funds a number of comparative research projects. \u201cThere is one principal investigator from Duke and one from the NCSU College of Vet Med,\u201d says Eward. \u201cWe have two ongoing clinical trials for dogs with osteosarcoma. One offers the drug bortezomib as single agent therapy and the other trial involves an old drug called niclosamide. This drug has solid anticancer properties, but has never been usable for this because of its poor chemistry. A physical chemist named David Needham has developed a new formulation of the drug, which is able to be soluble in the bloodstream.\u201d<\/p>\n

The other schools involved in canine comparative oncology research with the V Foundation include University of Pennsylvania School of Veterinary Medicine, teamed with Abramson Cancer Center at UPENN; University of Wisconsin Madison School of Veterinary Medicine, with Flint Animal Cancer Center; and University of Minnesota College of Veterinary Medicine.<\/p>\n

Learn More<\/h3>\n

Read Fundamentals of Surgical Oncology in Small Animals<\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"

Five veterinary schools are receiving research grants from the V Foundation for Cancer Research in an innovative grant-making program that aims to accelerate research in the field of canine comparative oncology.<\/p>\n","protected":false},"author":11,"featured_media":15741,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"iawp_total_views":30,"footnotes":""},"categories":[342],"tags":[],"class_list":["post-15739","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-digital-exclusive","column-digital-exclusive","clinical_topics-news"],"acf":{"hide_sidebar":false,"hide_sidebar_ad":false,"hide_all_ads":false},"yoast_head":"\nVeterinary Schools Receive Grants to Treat Cancer in Dogs | Today's Veterinary Practice<\/title>\n<meta name=\"description\" content=\"Five veterinary schools received V Foundation grants that aim to accelerate research in the field of canine comparative 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