{"id":5291,"date":"2019-04-03T12:39:14","date_gmt":"2019-04-03T19:39:14","guid":{"rendered":"https:\/\/todaysveterinarybusiness.com\/?p=5291"},"modified":"2022-03-15T19:20:20","modified_gmt":"2022-03-15T19:20:20","slug":"once-a-day-proin-earns-fda-approval","status":"publish","type":"post","link":"https:\/\/navc.sitepreview.app\/todaysveterinarybusiness.com\/once-a-day-proin-earns-fda-approval\/","title":{"rendered":"Once-a-day Proin earns FDA approval"},"content":{"rendered":"

The U.S. Food and Drug Administration has approved an extended-release version of the twice-a-day canine incontinence drug Proin.<\/p>\n

Given daily, Proin ER (phenylpropanolamine hydrochloride extended-release) tablets are indicated for the control of urinary incontinence<\/a> due to urethral sphincter hypotonus in dogs.<\/p>\n

The new prescription medication, manufactured by Pegasus Laboratories Inc., comes in 18-, 38-, 74- and 145-milligram tablets.<\/p>\n

A clinical field study found the most common adverse reactions to be vomiting, body weight loss, hypertension and diarrhea, according to the FDA<\/a>. The drug should not be given to dogs weighing less than 10 pounds.<\/p>\n

Original Proin received FDA approval in 2011.<\/p>\n","protected":false},"excerpt":{"rendered":"

The extended-release drug is formulated to control urinary incontinence in dogs.<\/p>\n","protected":false},"author":45,"featured_media":5292,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"iawp_total_views":0,"footnotes":""},"categories":[90],"tags":[],"class_list":["post-5291","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-online","column-news","clinical_topics-news","clinical_topics-veterinary-products"],"acf":{"hide_sidebar":false,"hide_sidebar_ad":false,"hide_all_ads":false},"yoast_head":"\nOnce-a-day Proin earns FDA approval | Today's Veterinary Business<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Once-a-day Proin earns FDA approval\" \/>\n<meta property=\"og:description\" content=\"The extended-release drug is formulated to control urinary incontinence in dogs.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/navc.sitepreview.app\/todaysveterinarybusiness.com\/once-a-day-proin-earns-fda-approval\/\" \/>\n<meta property=\"og:site_name\" content=\"Today's Veterinary Business\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/todaysveterinarybusiness\" \/>\n<meta property=\"article:published_time\" content=\"2019-04-03T19:39:14+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2022-03-15T19:20:20+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/navc.sitepreview.app\/todaysveterinarybusiness.com\/wp-content\/uploads\/sites\/2\/2019\/04\/Incontinence.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1300\" \/>\n\t<meta property=\"og:image:height\" content=\"680\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"Louise S. Dunn\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@tvbpublication\" \/>\n<meta name=\"twitter:site\" content=\"@tvbpublication\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Louise S. Dunn\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarybusiness.com\\\/once-a-day-proin-earns-fda-approval\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/navc.sitepreview.app\\\/todaysveterinarybusiness.com\\\/once-a-day-proin-earns-fda-approval\\\/\"},\"author\":{\"name\":\"Louise S. 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